What is the LED skin rejuvenation? LED skin rejuvenation is the interaction of light, delived through Light Emitting Diodes(LED),to activate cell receptors causing them to produce collagen or multiply.One of the original applications for LEDS was PhotoDynamic therapy(PDT),using photo-activated creams for the treatment of actinic keratosis and pre-cancerous lesions. How are LEDS different from Laser and Intense Pulsed Light(IPL)therapy? Other light-based skin therapies including intense pulsed light and laser treatments rely on thermal injury to the skin's collagen, water or blood vessels to create changes in the skin appearance.LED skin rejuvenation does not rely on thermal energy and the related tissue trauma to effect change. There fore, patients are not subject to the variables associated with wound healing.